Dynamic cluster formation determines viscosity and diffusion in dense protein solutions
نویسندگان
چکیده
منابع مشابه
Impact of aggregate formation on the viscosity of protein solutions.
Gaining knowledge on the stability and viscosity of concentrated therapeutic protein solutions is of great relevance to the pharmaceutical industry. In this work, we borrow key concepts from colloid science to rationalize the impact of aggregate formation on the changes in viscosity of a concentrated monoclonal antibody solution. In particular, we monitor the kinetics of aggregate growth under ...
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Vii. the Viscosity of Some Protein Solutions
In the following work the same general methods were employed as in that already published by Martin and Chick [1912] upon the viscosity of solutions of caseinogen. In the present instance an investigation was made of the influence of (1) concentration of protein, and (2) temperature, upon the viscosity of solutions of pure crystallised eggand (horse) serum-albumin. For purposes of comparison, a...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2019
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1817564116